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Taking GLPs = Saggy Bag of Bones The Importance of Preserving Lean Mass and Bone Density While Using GLP-1 Medications




So, you’ve jumped on the GLP-1 medication bandwagon, taking semaglutide (Ozempic) or tirzepatide (Mounjaro) to shed some pounds, feel healthier, and maybe even get your blood sugar levels under control. Kudos to you! These meds are a game-changer, with the power to help you lose weight, improve your insulin sensitivity, and generally feel like a more vibrant version of yourself.

But—and here’s the plot twist—weight loss isn’t all sunshine and rainbows. Especially when you lose more than 10% of your body weight, you're not just waving goodbye to fat—you might be saying “see ya” to some muscle and bone too. And if you’re a premenopausal or menopausal woman, well, the risk of losing that precious lean mass and bone density just got even higher.

Let’s dive in, shall we?


The Hidden Risk: Losing More Than Just Fat

First things first: GLP-1 medications like semaglutide and tirzepatide work wonders by curbing your appetite, slowing digestion, and helping your body burn fat. It's like a little magic wand that helps you drop pounds without feeling like you’re starving. But—and here's the thing—when you lose weight too quickly or without focusing on lean mass, you could find that you're shedding muscle and bone density along with the fat. Yikes, right?

Here’s what happens when you lose more than 10% of your body weight:

  1. Lean Mass Loss: Sadly, weight loss isn’t exclusive to fat. Your body can break down muscle tissue for fuel, especially if you're in a calorie deficit and not paying attention to how much protein you’re eating.

  2. Bone Density Decline: Losing weight too quickly can also lead to weaker bones. That’s because your bones need stress (from things like strength training) and nutrients (like calcium and vitamin D) to stay strong. Without these, you could be at risk of osteoporosis.

  3. Premenopausal and Menopausal Women: Extra Care Needed

Now, if you’re a premenopausal or menopausal woman, listen up! You’re at additional risk when it comes to losing muscle and bone. Why? Because your hormones are undergoing seismic shifting!

  • Estrogen and Bone Health: Estrogen is like the fairy godmother of bone density. When estrogen levels drop during menopause, bone resorption (bone breakdown) picks up, and bone formation slows down. The result? Weaker bones that can be more prone to fractures.

  • Muscle Loss: Estrogen also helps with muscle preservation. As estrogen drops, muscle mass can decline too. Combine that with the calorie restriction from weight loss meds, and you’ve got a recipe for sarcopenia (muscle loss) = Saggy Bag of Bones!

So, what can you do? Keep reading, because REVIVE Infusions & Wellness has a game plan for you!


The Secret to Success: Protein, Strength Training, and Hormone Optimization

Alright, now that we know the risks, let’s talk about solutions! Ready for some muscle-saving magic? Here’s how you can preserve your lean mass and keep your bones strong while using GLP-1 medications:


1.     Prioritize Protein—Your Muscle’s BFF

a. Protein is the essential nutrient when it comes to muscle preservation. Think of it as the brick and mortar that keeps your muscles from crumbling like a poorly constructed

house.

b.   How much protein? A great goal is about 1 to 1.5 grams of protein per pound of your desired body weight. For example, if your goal weight is 150 pounds, aim for 150 to 225 grams of protein a day. Sounds like a lot? Don’t worry, it’s totally doable! Just start adding protein-rich foods to every meal—think chicken, fish, tofu, eggs, lentils, and of course, don’t forget your trusty protein powder (because, let’s be real, who doesn’t love a good protein shake?). It’s all about making protein a priority, and soon enough, you’ll be hitting those targets like a pro!

 

II.     Lift heavy stuff: You don’t need to become a bodybuilder, but aim to do at least 2-3 strength training sessions per week.

a. Focus on compound exercises (like squats, deadlifts, and push-ups) that work multiple muscle groups. These exercises help increase bone mineral density and keep those muscles nice and firm.

 

b.     Progressive overload: As you get stronger, gradually increase the weight or resistance. Your muscles will thank you—and your bones will too!


III. Optimize Hormones to Keep the Lean Mass and Bone Density

Optimizing your sex hormones is the other secret sauce that’ll take your weight loss game from “meh” to “wow!” (Trust me, it’s a big deal.) Why? Because your sex hormones (like estrogen, testosterone, and progesterone) are like the backstage crew of a Broadway show—without them, the whole production falls apart. These hormones don’t just influence your mood and energy levels (though they certainly do that); they’re also responsible for lean muscle, bone density, and fat distribution. So, if you want to lose weight the right way, it’s time to get serious about those hormones—because when they’re in balance, you can kiss muscle loss and brittle bones goodbye!

Let’s break it down, shall we?


1. Lean Mass and Hormones: The Power Duo You Need

Alright, we’ve all heard it: muscle is the metabolic engine of the body. The more muscle you have, the more calories you burn—even when you’re binge-watching Netflix in your PJs. But here’s the kicker: if you’re losing weight too quickly or not watching your muscle intake, you could end up sacrificing lean muscle along with the fat. Nooo! That's like throwing out the best part of the pizza—nobody wants that.

  • Testosterone is the muscle superhero for both men and women. It helps you build muscle, burn fat, and generally be awesome at life. Low testosterone means muscle loss, belly fat, and feeling less-than-invincible. Not cute.

  • Estrogen is like your muscle bodyguard. It helps preserve lean muscle, especially for women. When estrogen levels drop (hello, menopause!), muscle mass can start to shrink, which means more fluffy and less toned.

By optimizing your hormones (we'll get to how in a second), you’ll hold onto that muscle like it's your favorite pair of jeans that always fit just right.

2. Bone Density: Protect Those Precious Bones!

Okay, let’s talk about bones. You’ve got to keep those puppies strong, especially as you lose weight. Here’s the problem: when you drop pounds—especially too quickly—you can lose bone density along with fat. And if you're not paying attention to your hormones, that can lead to osteoporosis, which sounds like something you definitely don’t want to be dealing with later.

  • Estrogen is the bone-strengthening hormone. It’s the one that keeps bones strong by encouraging bone-building cells and discouraging bone-breakdown cells. When estrogen takes a nosedive during menopause, bones can weaken, and fractures can happen more easily. Not ideal.

  • Testosterone also plays a role in bone health. Low testosterone can contribute to bone loss in both men and women. So, to keep your bones sturdy like a fortress, you need to optimize those hormones.

3. Weight Loss Magic (With a Side of Hormone Help)

You want to lose fat, right? Well, hormones like insulin, leptin, and ghrelin all work together to regulate hunger, fat storage, and how your body uses energy. GLP-1s work wonders here, but if your testosterone and estrogen are out of whack, it’s like trying to drive a car with a flat tire—you’re not going to get very far.

  • Testosterone helps boost metabolism and burn fat, so if your levels are low, you could be storing fat—especially around the belly. Not the kind of weight you want to be losing, right?

  • Estrogen helps regulate where your body stores fat. When your estrogen drops, fat tends to hang out around your waist. But if you optimize your estrogen, you’ll find fat distribution is more in balance—and the fat around your belly doesn’t get the VIP seat.

So, by keeping those hormones happy, you’ll burn fat faster and more effectively, making your weight loss journey that much smoother.

4. How to Optimize Your Hormones While on GLP-1s: Hormone Hacks to the Rescue!

Okay, so how do we get our hormones into tip-top shape while we’re rocking GLP-1s?

For Men:

  • Testosterone: If you’re feeling sluggish, have trouble building muscle, or your energy levels are low, your testosterone could be slacking. Consider testosterone replacement therapy (TRT) or natural ways to boost it, like strength training and eating healthy fats (hello, avocado!). This will keep your muscle mass in check and your fat-burning furnace running strong.

For Women:

  • Estrogen: When you hit menopause, estrogen drops, and that’s when muscle loss and bone density issues can creep in. Consider hormone replacement therapy (HRT) to restore balance. This helps maintain muscle, prevent bone loss, and keep those curves in check.

  • Progesterone: This hormone isn’t just for your cycle; it helps balance out estrogen and supports better sleep. And who doesn’t need a good night’s sleep for recovery and weight loss? Consider bioidentical progesterone or natural supplements to improve sleep and reduce stress.

For Everyone:

  • Testosterone: Boosting testosterone helps both men and women build muscle, burn fat, and feel like a million bucks. You can do this with natural testosterone boosters (like exercise and stress management) or TRT if needed.

5. Growth Hormone Secret Weapon: Sermorelin

Here’s a little something extra for you: the Growth Hormone (GH). You may not hear about it as much, but GH is the ultimate multitasker. It helps preserve muscle, supports bone health, burns fat, and even boosts recovery after workouts. As you age, GH levels naturally drop, and that’s when things start to go south.

Sermorelin, a growth hormone secretagogue that stimulates the release of GH. Think of it like sending your pituitary gland a “Wake up and get to work!” memo. This helps preserve lean mass, increase bone density, and speed up recovery. It’s like a magic elixir for your muscles and bones!

When you combine Sermorelin with your GLP-1 meds, you’ve got a supercharged weight loss and muscle-preserving combo that work in synergy to provide game changing results!


The Takeaway: Keep Your Lean Mass and Bone Health in Check

So, to wrap things up: GLP-1 medications are fantastic for weight loss, but if you're not careful, you could end up losing more than just fat—you might also lose muscle and bone. By prioritizing protein, strength training, and hormone optimization, you can preserve that hard-earned muscle and keep your bones strong, even while you shed pounds.

And for the premenopausal and menopausal women out there, don’t forget the importance of estrogen, growth hormone, and taking the right steps to protect your lean mass. With a little planning, you can lose weight the right way, feeling strong and vibrant every step of the way.

And for that extra muscle-preserving, bone-building boost? Sermorelin could be your secret weapon. Now, let’s get to work—your lean, strong, and healthy future is waiting!'


Don’t want to be a Saggy Bag of Bones?

Don’t worry REVIVE Infusions & Wellness we’ve got you! Our medical-assisted weight loss program is paired with wellness coaching providing you the tools and strategies to ensure your success! With a little protein, some strength training, and a sprinkle of hormone optimization, you can rock this weight loss journey while protecting your muscles and bones. And just to keep things interesting, we’ll even throw in a little secret weapon called Sermorelin to help you supercharge your lean mass!

Happy lifting, eating, and hormone optimizing! 💪🎯 💧 🧬


Discover More about GLPs and Medical Weight Loss at www.reviveinfusewell.com







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